Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core: Inhibition of HIV-1 infection caused by disrupting CypA-CA interactions is dependent on TRIM5αhu expression, which is normally unable to efficiently bind core due to CypA steric hindrance.

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Cyclophilin A Prevents HIV-1 Restriction in Lymphocytes by Blocking Human TRIM5α Binding to the Viral Core: Inhibition of HIV-1 infection caused by disrupting CypA-CA interactions is dependent on TRIM5αhu expression, which is normally unable to efficiently bind core due to CypA steric hindrance. submitted by /u/SecretAgentIceBat
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